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GE Aviation, headquartered in Evendale, is a major manufacturer of aircraft engines globally.In 2010, EPISCENTER, a new R&D center for the corporation to be located in Dayton, was announced by the Third Frontier program.Ohio is considered a center of science and industry, with museums dedicated to such in Columbus, COSI, the Great Lakes Science Center in Cleveland, the Imagination Station in Toledo, and the Boonshoft Museum of Discovery in Dayton.The state includes many historically strong industries, such as banking and insurance, which accounts for 8% of the gross state product, motor vehicle manufacturing, research and development, and steel production, accounting for 14-17% of the nation's raw output.The state had a projected GDP of 6.1 billion in 2013, up from 517.1 in 2012, and up from 501.3 in 2011, according to the Bureau of Economic Analysis.In 2013, Ohio was ranked in the top ten states for best business climate by Site Selection magazine, based on a business-activity database.Nextant Aerospace has manufacturing facilities at the Cuyahoga County Airport.Defense systems play a smaller role in the industry.
Notable defense contractors include Goodyear Tire and Rubber Company in Akron, Lockheed Martin in Akron, which won a contract to develop a space-ship in 2003 and produces the vertical launch ASROC missile, Columbus-based Zyvex Performance Materials develops the Piranha Unmanned Surface Vessel.The state was edged out only by Texas and Nebraska for the 2013 Governor's Cup award from the magazine, based on business growth and economic development.A new report by the Quantitative Economics and Statistics Practices (QUEST) of Ernst & Young in conjunction with the Council On State Taxation (COST), ranks Ohio as third in the nation for friendliest tax environment.Welltower, an S&P 500 company headquartered in Toledo, is a major healthcare real estate firm.
VRI, one of the nation's largest in-home medical health monitoring solutions companies, recently In 2011, Dayton was ranked the #3 city in the United States for excellence in health care.
Biotech research and development employs directly 12,415 residents, while agricultural bioscience contributed the largest economic impact, at .7 billion.